Study shows : elderly females with dense breasts are higher risk of breast cancer .
UC Davis Comprehensive Cancer Center researcher Diana Miglioretti is co-senior author of a replacement study that shows women seventy-five and elderly who have dense breasts are at higher risk of breast cancer.
UC Davis carcinoma researcher Diana Miglioretti helped lead a study showing breast density could also be a cancer risk in older women
The research fills an information opening and can affect whether older women receive carcinoma screening mammography.
The study was published on 26th August 2021 in JAMA Network Open, a web open access journal published by the American Medical Association. Researchers examined data from quite 193,000 women age sixty-five and older, including quite seventy thousand who were a minimum of seventy-five. They found a positive association between breast density and carcinoma risk.
“This study provides evidence that breast density remains an important risk believe older women and can be included in risk prediction models that also consider anticipation to help identify women who may benefit most from continued screening,” Miglioretti said.
Miglioretti teamed up with co-senior author, Dejana Braithwaite, associate director of population sciences at the University of Florida Health Cancer Center and a professor within the University of Florida Institute on Aging.
“Our goal is to develop the evidence that helps personalize carcinoma screening for older females,” said Braithwaite. “Older women who are in healthiness and have dense breasts may consider a screening mammogram whilst they age beyond the screening recommendations for average-risk women.”
Physicians have long recognized that ladies with denser breasts are at increased risk of invasive carcinoma, but so far, virtually no data existed for ladies age seventy-five and older.
Right now, the United States of America Preventive Services Task Force, or USPSTF, an independent panel of national experts on disease prevention and evidence-based medicine, doesn’t recommend for or against mammography screening after age seventy-four. The task force says evidence to weigh risk versus benefit has been insufficient for a definitive recommendation.
Breast density could also be a measure of the number of fibrous or glandular tissue compared with fat, with less dense breasts containing more fat. Roughly half of women ages forty to seventy-four have dense breasts. The breasts of ageing women subsided dense over time, although nearly a 3rd of all women age sixty-five and older still have dense breasts, Braithwaite said.
The USPSTF recommends a mammogram every two years for women in the fifty to seventy-four age group. American Cancer Society recommendations are slightly different, with annual mammograms suggested for females forty-four and older, then biennially after age fifty-five for females who are in healthiness.
Physicians note that not all older women would enjoy screening mammography, especially those with serious medical conditions.
The study analyzed data from the carcinoma Surveillance Consortium and specifically examined breast density as a carcinoma risk think about two groups of girls -; those ages sixty-five to seventy-five and those who are seventy-five and older. Data were collected from women in New Hampshire, Vermont, North Carolina, the San Francisco area, Washington, New Mexico and Colorado.
While researchers found that age is that the strongest risk factor for carcinoma, women with dense breasts have a better risk of carcinoma than women with fatty breasts. And the risk increases with increasing breast density. For example, in women sixty-five to seventy-four years old, the team found an increased five-year risk of carcinoma that ranged from 11.3 per 1,000 women in groups with fatty breasts to 23.7 per 1,000 females in groups with dense breasts.
“The thirty per cent to thirty-two per cent of aged women with high breast density should ask their health care provider whether having high breast density sufficiently increases their risk to warrant ongoing screening mammography.”
Karla Kerlikowske co-author and member of UCSF Helen Diller Family Comprehensive Cancer Center.
SOURCE
https://www.news-medical.net/news/20210828/Older-women-with-dense-breasts-are-at-higher-risk-of-breast-cancer-study-shows.aspx