Using nanobots and robotics to increase the likelihood that IVF will succeed


Using nanobots and robotics to increase the likelihood that IVF will succeed

Using nanobots and robotics to increase the likelihood that IVF will

Artificial Reproductive Techniques (ART) treatments have greatly improved in terms of success rates and safety thanks to recent technological developments in the field of fertility therapy. The micro-assisted fertilization approach known as intracytoplasmic sperm injection (ICSI) has been used in clinical settings for more than 20 years.

While the insemination of eggs process used in IVF entails combining thousands of motile sperms with each egg in a dish in the hopes that the sperm and egg would interact biochemically. However, relatively few eggs become fertilized following incubation when either the egg or the sperm components are inadequate. ICSI, however, has been demonstrated to be of great benefit in situations of oligospermia (low sperm count), teratozoospermia (abnormal sperm morphology), and sperm transport disorder, when sperm production is adequate but sperm motility, quality, and concentration are diminished.

Ø Changes to ICSI Technique

With ICSI and IVF, the number of viable sperm needed for egg fertilization has decreased from 100 to just one, revolutionizing the treatment of male infertility. Due to this, men with low or no sperm counts have recently been able to produce viable sperm for egg fertilization using aggressive new approaches. By choosing the best sperms and embryos, the application of artificial intelligence, nanotechnology, laser-assisted hatching, and robotic ICSI methods have revolutionized the results.

1. Artificial intelligence

 At this time, the technology built on artificial intelligence, which is still in clinical testing, has a very high predicted success rate in determining the best embryo in terms of its growth pattern. In this method, an AI system examines a vast quantity of data (hundreds of photos of each embryo) and determines which embryos have the best chance of becoming foetal hearts. The best-scoring embryo, which has the best chance of developing into a healthy foetus, can then be chosen for tr2. Nanobots and robotic technology 

2. Nanobots and robotic technology 

Automation of ICSI by robotic and nanotechnology has made it possible to analyze oocyte penetration in real-time by choosing the best sperm or embryo. The best sperm cell is chosen and transported via nanotechnology until it enters the egg, where it is then implanted to create a healthy embryo. In contrast, in robot-assisted ICSI, the system carries out highly reproducible sperm insertion into an oocyte, picoliter volume sperm aspiration, robotic sperm immobilization, and visual tracking of the single sperm. Numerous such trials have been carried out successfully with a high success rate of above 90% and survival rate, requiring little human involvement.

3. Laser-Assisted Hatching 

In some circumstances, it is also possible that the embryo implantation in the uterus fails for arbitrary reasons. In these situations, the best embryo is selected, and it undergoes a process called "laser aided hatching" before being implanted. Scientifically, laser-aided hatching enables to make of a small opening on the outer layer of the embryo because in some circumstances the outer layer of the embryo may thicken abnormally, making it simpler for the embryo to implant better to the endometrium.

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