How to Increase Success of IVF: Essential Tips & Latest Advances
Wondering how to increase success of IVF? IVF success isn’t guaranteed—but with the right clinic, timing, lifestyle habits, technology, and support, your chances can improve significantly.
🏥 Choose the Right Clinic & Lab
- Select a clinic known for high success rates, advanced embryology labs, and experienced staff. Lab quality strongly affects outcomes.([turn0search7])
- Look for clinics that use blastocyst-stage transfers, soft catheters, ultrasound guidance, and hyaluronic acid media during embryo transfer.([turn0search28])
⏰ Optimise Timing of Embryo Transfer
- Emerging research (e.g. PCX molecule levels) suggests identifying the **optimal mid-luteal window** improves implantation—from ~18% to ~53% success.([turn0news21])
🤖 Use AI & Advanced Embryo Selection
- AI platforms like AIVF EMA score embryos based on time-lapse imaging—boosting implantation accuracy by ~38% and reducing failed cycles.([turn0search26])
- Time-lapse imaging combined with machine learning can increase prediction of embryo viability by 12%–29%.([turn0academia30])
🧬 Genetic Testing When Indicated
- Preimplantation genetic testing (PGT‑A) helps select chromosomally normal embryos, especially useful for women over 35 or with prior losses, boosting implantation success.([turn0search23])
🥗 Support Body & Lifestyle Before IVF
- Start preparing at least **3 months before IVF**: follow a Mediterranean-style diet, maintain BMI 19–25, avoid alcohol and smoking.([turn0search1][turn0search0])
- Regular moderate exercise, stress management, quality sleep, prenatal vitamins (with folic acid), and supplements like CoQ10 or myo-inositol may support egg quality.([turn0search9][turn0search12][turn0search24])
👨⚕️ Male Partner Preparation Matters
- Sperm quality influences IVF outcome—men should adopt a healthy diet, avoid heat, manage stress, and prepare sperm ~3 months before retrieval.([turn0news13])
💊 Medication & Luteal Support
- Use appropriate ovarian stimulation protocols tailored to age and ovarian reserve (e.g. AMH/AFC-guided dosing). GnRH antagonist protocols often offer better results.([turn0search27][turn0search2])
- Luteal phase support with progesterone—especially with GnRH agonist addition—improves live birth rates by up to 16%.([turn0search25])
📈 Manage Expectations: Persistence Helps
- First-cycle success is ~30% in women under 35—but rates climb to ~65% by the sixth attempt. Understanding the long-term trajectory helps set realistic goals.([turn0news19])
📊 Summary Table
| Strategy | Benefit |
|---|---|
| Top-tier clinic and lab | More accurate embryo handling & transfer |
| Optimal timing (PCX window) | Better implantation chance |
| AI-based embryo selection | Higher pregnancy accuracy per cycle |
| PGT-A when indicated | Lower miscarriage risk, higher success |
| Lifestyle prep | Improved egg and sperm quality |
| Male partner health | Supports sperm viability |
| Luteal support | Enhances implantation success |
| Multiple attempts | Cumulative success increases over cycles |
✅ Takeaway
Increasing IVF success requires a multi-pronged strategy—choosing a skilled clinic, optimising timing, using AI/genetic tools wisely, preparing body and partner, and supporting luteal phase. Persistence and careful planning can raise your odds significantly.
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