IVF Success Rates By Age

 “IVF Success Rates By Age”

IVF success by age ichhori.com





In vitro fertilisation (IVF) is already almost a household term. In vitro fertilisation (IVF) is the process of combining eggs and sperm outside of the body in a laboratory. The embryo or embryos are placed in the uterus once they have been formed. IVF is a difficult and expensive treatment, and only around 5% of infertile couples opt for it. Except in situations of total tubal blockage, IVF is never the initial step in the treatment of infertility. It's only used in instances where other procedures have failed, such as fertility medications, surgery, or artificial insemination.

Infertility is a complex problem that affects up to 15% of couples who are attempting to start a family. Depending on your specific circumstance, in-vitro fertilisation may be used to address a variety of infertility issues. The exorbitant expense of IVF, as well as the mental and physical toll it takes, may make women wonder if it's worth it.

Success Rates for IVF

IVF is typically successful, particularly for women under the age of 35 or for those who use donor eggs. IVF success rates are determined by a variety of factors, including the cause of infertility, the location of the procedure, and age. According to a 2016 report:

  • Pregnancy was obtained in 27.3% of all cycles on average (higher or lower depending on the age of the woman).

  • On average, 22.2% of cycles culminated in live births (greater or lower depending on the age of the woman).

The Impact of Female Age

The chances of a live delivery from any given IVF cycle is primarily determined by the age of the woman whose eggs are being utilised. Even for the healthiest and youngest women, the majority of IVF cycles fail. Delaying treatment carries a cost that rises with the length of time spent waiting. Waiting seven years, for example, reduces the chances of any particular IVF cycle working from roughly 48% to 2-4%. Younger women have a higher chance of having a successful pregnancy. Because the odds of a successful pregnancy are believed to be extremely low, IVF isn't typically suggested for women beyond the age of 42. Between 2014 and 2016:

  • 29% of IVF procedures resulted in a live delivery for women under the age of 35.

  • For women aged 35 to 37, the percentage was 23%.

  • 15% for women between the ages of 38 and 39.

  • For women aged 40 to 42, the rate is 9%.

  • 3% for women between the ages of 43 and 44.

  • 2% for women over the age of 44.

IVF success rates under 35

Women under 35, especially those in their 20s, are thought to have greater success rates in terms of age because this is when they are most fertile. Women who do not have any recognised fertility difficulties have a 20% pregnancy success rate, but if they are experiencing infertility issues such as a lack of eggs, hereditary illness, partner infertility, or a same-sex relationship, they will opt for IVF, which has a higher success rate. (CDC)

If a woman has never been pregnant before and is under the age of 35, she is more likely to conceive in 32% of cases. If a woman has already had a child, there is a 37% chance that an IVF cycle would succeed and result in a successful pregnancy before the age of 35. If a woman is in her 20s, she has a 34% chance of having two or more children after an IVF cycle. Women under the age of 35 have a 52 percent probability of becoming pregnant after just one round of IVF, according to research.

IVF success rates over 40

Women over the age of 40 are less likely to conceive; in previous generations, it was nearly impossible for women over the age of 40 to have a baby. However, thanks to new technologies and innovations such as assisted reproductive technology (ART), it is now possible for women over the age of 40 to have a baby and enjoy motherhood even as they approach menopause. 

  • For 40 year olds, there is a 20% probability of having a successful IVF cycle and a 14% chance of having a live delivery.

  • For 41, IVF cycles has a 15% probability of success and a 10% likelihood of a live delivery.

  • For 42, the IVF cycle and live birth rates are 12% and 7%, respectively.

  • After 43 years, the percentage drops to 8%, with only 3% of pregnancies ending in a healthy birth.

  • For 44 year olds, there is a 6% probability of IVF resulting in pregnancy and a 3% likelihood of a live delivery.

  • Finally, women over 45 have just a 3% probability of becoming pregnant with IVF and a 1% chance of having a live delivery.

Undergoing only one round of IVF to become pregnant at the age of 40, limits the odds of becoming pregnant to just 8%. As a result, it is advised to go for at least two rounds. Also, because every human body has its own inclinations and many other factors have a significant influence in the success rate of this therapy, it is vital to note that this data should not be used to predict your own outcomes.

IVF success rate by number of embryos

An embryo, the number and quality of the embryo, is one of the most significant elements that determines the success rate. The majority of treatment failures are caused by the use of low-quality embryos. The PGD (pre-implantation diagnosis) technique is used by doctors to determine, differentiate, and further select the appropriate embryo. There are embryos that appear efficient on the outside but lack factors needed for pregnancy. On the other hand, embryos that do not appear efficient on the outside are most likely to have all the efficiency required for successfully.

Single-embryo transfer and multiple-embryo transfer both have about the same success rate. Regardless of how many embryos are utilised for IVF, the risk element must be considered. The success rate of "single embryo transfer" was determined to be 45%, while "double embryo transfer" was calculated to be 42%.

The Impact of Donor Eggs, Donor Sperm or a Surrogate

While it may be difficult for patients to consider, utilising donated eggs or sperm during IVF can greatly increase the chances of a successful cycle. The same is true when using a gestational carrier or surrogate, which has a success rate of about 70% every cycle.

The Impact of a Patient’s Condition or Diagnosis

Medical problems can have an impact on a woman's fertility. Other medical problems are made worse by IVF therapy, and in some circumstances, a pregnancy should not be carried out for the sake of the female since it may endanger the patient's life. Medical conditions that affect the fertility of a woman include hypertension, diabetes mellitus, cardiovascular diseases like coronary heart disease and comorbid conditions like obesity, dyslipidemia, glucose intolerance; epilepsy, and thyroid disorders. 


Infertility is a very personal issue for many couples. Relationship dynamics, family support, religious views, financial position, lifestyle, and mental health all play a part in deciding whether or not to use IVF. Despite the fact that statistical odds can be considered into plans, not everyone is a statistic figure. The outcome of a project might be unexpected. Finally, decisions should be driven by internal motivation.


Sources:

  1. https://advancedfertility.com/2020/09/16/fertility-after-age-40-ivf/

  2. https://advancedfertility.com/2020/09/11/age-and-ivf-in-vitro-fertilization-statistics/

  3. https://www.verywellfamily.com/what-are-the-chances-for-ivf-success-1960213#a-word-from-verywell

  4. https://www.indiraivf.com/ivf-success-rates-by-age-and-number-of-embryos/

  5. https://www.fertilityiq.com/ivf-in-vitro-fertilization/ivf-success-rates#the-impact-of-a-patients-condition-or-diagnosis




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