Choosing the Best Eggs for IVF: What You Should Know
Based on Ichhori (October 2022), enhanced with expert insights.
Key Factors Influencing Egg Suitability for IVF
- Age of the woman: Egg quality declines sharply after age 35, increasing chromosomal abnormalities and reducing success chances. ([turn0search8], [turn0search6])
- Ovarian reserve markers: Tests like AMH levels and antral follicle count help assess egg quantity, though they don’t precisely predict egg quality. ([turn0search18], [turn0search15], [turn0search6])
- Underlying health and lifestyle: Factors like obesity, stress, and hormonal imbalances can impair egg quality. Supplements such as CoQ10, DHEA, and vitamin D may support egg health. ([turn0search17], [turn0search6], [turn0search18])
How Many Eggs Are Ideal?
Aiming for around 10–12 mature eggs increases the chance of obtaining at least one genetically normal embryo—typically translating to a ~65% chance of pregnancy per embryo transfer. Older women might require more eggs to reach similar chances. ([turn0search3], [turn0search7])
Egg vs. Embryo Quality
Egg quality is foundational—poor-quality eggs often result in failed fertilization or chromosomal issues. While embryo quality ultimately affects implantation, it starts with an egg's health. IVF labs may use grading systems, but success still depends on viable embryo development. ([turn0search1], [turn0search0])
When to Consider Donor Eggs or Alternatives
If ovarian reserve is low or egg quality is compromised—especially in older patients—using donor eggs may significantly improve IVF success rates. ([turn0news10], [turn0search4])
Summary Table
| Factor | Importance |
|---|---|
| Age | Key determinant—linked to egg chromosomal health and overall potential |
| Ovarian Reserve | Tests like AMH/AFC gauge quantity—but quality still matters |
| Lifestyle & Health | Impact egg quality; supplements may offer support |
| Egg Count | 10–12 mature eggs yield optimal success; more needed if older |
| Egg vs Embryo | Quality eggs produce better embryos; labs aid grading but can't overcome poor egg quality |
Why It Matters
Choosing the best eggs for IVF isn't just about numbers—it's about age, health, and biology. Recognizing these factors helps set expectations, guide treatment planning, and optimize outcomes. When necessary, alternatives like egg donation should be considered under expert guidance.