Which COVID vaccine is best?

The best vaccine is the one you can get right now - Times of India

COVID-19 affects everyone in diverse ways. Most infected people will have mild to moderate illness and get well without hospitalization.


Most common symptoms:


  • Fever
  • Dry cough
  • Fatigue


Least common symptoms:


  • Aches and pains
  • Painful throat
  • Diarrhea
  • Conjunctivitis
  • Headache
  • Taste or smell is not sensed
  • Rashes on the skin, or marks on fingers or toes


Facts about COVID-19:

  • By being aware about the facts of COVID-19 signs, how the virus spreads and what you can do to end it will help guard you and your society.
  • COVID-19 is a recent virus that has spread rapidly to many countries around the world counting in Southern Africa.
  • There is a lot of half-truths about COVID-19 so it’s vital to check information has come from a consistent source such as the World Health Organization or your government health authority.
  • Most people who have COVID-19 will have a mild form of  illness and recover without professional medical care. About 8 out of every 10 people with COVID-19 will have mild signs. Around one in six people will become ruthlessly ill and require hospital care. Scientific modeling proposes that around 1 in 100 people who get COVID-19 will die.
  • Anyone can get COVID-19, despite of race or skin color. Older people and people with other health situations, like asthma, heart diseases, and diabetes, are more at risk of getting critically ill. 

With the raise in the number of coronavirus cases, India has become one of the adversely affected countries in the world. Below is the list of Indian vaccines:

  1. Covaxin
  2. Zydus Cadila's ZyCoV-D
  3. Oxford - AstraZeneca Vaccine
  4. Biological E
  5. Mynvax
  6. Gennova Biopharmaceuticals
  7. Covishield


According to recent data:

Countries Total doses        Doses per 100 people       Days since first dose













United Arab Emirates




Cayman Islands




United Kingdom




United States





















Despite numerous versions of the antibody tests on the market from various manufacturers, current evidence conveys antibody testing alone isn’t convincing for diagnosing a person with current or preceding COVID-19 or for predicting a patient’s persistent immunity. It mainly remains unclear how long antibodies live in a person’s body following a COVID-19 infection and how many antibodies are required to neutralize SARS-CoV-2 following another disclosure.


A vaccinated person is very probable to get a negative outcome from a serology test, even if the vaccine was successful and defensive. That’s because different serology tests sense antibodies to various parts of the virus.

Some tests detect antibodies to the spike protein of the virus, which is formed in reaction to viral infection or the vaccine. Others detect antibodies to a special part of the virus called the nucleocapsid protein, which are formed in response to infection but not by the present vaccines.

Vaccine experts consider side effects, efficacy rates, and how the vaccines pile up against the variations.

According to some, the Pfizer and Moderna vaccines have approximately 95% efficiency rates in clinical trials and are better than the Johnson & Johnson vaccine (with 66% efficiency) and the AstraZeneca vaccine (with 76% efficiency).

As per the White House, ninety percent of adults in America will be permitted for a COVID-19 vaccine by 19th April.

According to a Pew Research Center survey, 69% of Americans either have already been vaccinated or are planning to be vaccinated. That’s up from the 60% who alleged they’d get vaccinated last November. Still, 30% of respondents declared they would possibly or certainly not get a vaccine. The major causes given from the above were the worries regarding how efficiently the vaccines work, their side effects, and disbelieve in the rapid development procedure.

The answer of the question of best covid vaccine isn't clear. As per the data and obtainable vaccine supply, the best vaccine is the one that is available to you as early as possible.

According to recent data, Pfizer and Moderna COVID-19 vaccines are extremely effective at protecting against COVID-19. The Johnson & Johnson vaccine is effective in the same way for the prevention of ruthless COVID-19, and hospitalization and death from this virus.

Pfizer and Moderna: 

Pfizer Says Their COVID-19 Vaccine Is More Than 90% Effective

The foremost two COVID-19 vaccines in the U.S. make use of messenger RNA(mRNA). It is a molecule that informs human cells to create a piece of the spike protein that the coronavirus utilizes to attach and contaminate human cells.

How the FDA-authorized Moderna COVID-19 vaccine compares to Pfizer's |  Science News

The component from the vaccine rapidly breaks into smaller components and never enters the nucleus of the cell. Thus, it can't change the recipient's DNA.

The existence of the harmless spike proteins activates the immune system to generate antibodies and trigger T-cells that rises an immune response. Now, as the immune system is prepared, it is all set to respond rapidly whenever it senses the coronavirus in the body.

Johnson & Johnson: 

Third US vaccine could raise question: Which Covid-19 shots are best? |  Hindustan Times

The third vaccine to get emergency use endorsement in the United States utilizes another moderately new vaccine technology that squeezes a harmless adenovirus — a kind of virus that is responsible for the common cold — to convey the coronavirus spike protein directions. After many years of research, the foremost adenovirus vaccine — used to defend against the Ebola virus — was accepted in July 2020. Scientists reengineered the adenovirus in the COVID-19 vaccine so that it cannot duplicate and make the recipient ill, but it can still distribute the spike protein directions.


Coronavirus digest: UK finds 30 blood clot cases after AstraZeneca jab |  News | DW | 02.04.2021

This vaccine is not yet endorsed in the United States, but its producers intend to look for endorsement in the coming weeks. It functions in the same way as the Johnson & Johnson vaccine, except it, utilizes a reengineered adenovirus that specifically infects chimpanzees. 

Number of doses and gaps between doses of vaccines

  • Pfizer - Second dose after 21 days of the first dose.
  • Moderna - Second dose after 28 days of the dose.
  • Johnson & Johnson’s COVID-19 vaccine is considered to be distributed in one dose.
  • The AstraZeneca vaccine presently requires two doses given four weeks spaced out, but there is some ambiguity about how far apart the doses can be managed. The United Kingdom postponed the second dose to 12 weeks and one study recommended that the long delay may have reinforced the vaccine’s efficiency.

Side effects

Side Effects and COVID-19 Vaccines: What to Expect - COVID-19 - Johns  Hopkins Bloomberg School of Public Health

Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines presently approved by the FDA for emergency use comprise normally reported side effects of pain/soreness at the injection point, headache, fatigue, muscle aches, and nausea, which is generally fully subsided within 1-2 days after vaccination.

The Moderna and Pfizer vaccines contain some supplementary commonly reported side effects, like chills, fever, joint pain, and swollen lymph nodes. These side effects were more often known after the second dose, though they can occur after either dose. Since the Johnson & Johnson vaccine doesn’t need a second dose, there’s no enlarged risk of common side effects in the second dose. 

Thus, all three vaccines propose strong protection against the most severe and critical effects of COVID-19, the symptoms that tend people to die or need mechanical ventilation and treatment in an intensive care unit. 

Image Source: Google Photos

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